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Table 5 Correlation analysis of YAP1 promoter methylation with protein expression in Indian breast cancer patients

From: Aberrant Promoter Methylation of YAP Gene and its Subsequent Downregulation in Indian Breast Cancer Patients

YAP1 protein expression

YAP Promoter

   

Methylated (% within Protein expression)

Unmethylated (% within Protein expression)

Total

p value

OR (95% CI)

Present

13 (44.83%)

16 (55.17%)

   

Absent

84 (77.78%)

24 (22.22%)

   

Total (%)

97 (70.80%)

40 (29.20%)

137

0.001

0.232 (0.098 - 0.549)

YAP Promoter

YAP1 protein expression

   

Present

Absent

   

Methylated (% within methylation status)

13 (13.4%)

84 (86.6%)

   

Unmethylated (% within unmethylation status)

16 (40.0%)

24 (60.0%)

   

Total (%)

29 (21.17%)

108 (78.13%)

137

  
  1. p value p ≤ 0.005 is considered significant