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Table 3 Univariate analysis

From: FOXA1 and AR in invasive breast cancer: new findings on their co-expression and impact on prognosis in ER-positive patients

Characteristics

DFI

DSS

HR

CI

P

HR

CI

P

Age

0.98

0.96–1.00

0.110

1.00

0.98–1.03

0.727

Conservative vs Mastectomy

3.36

2.22–5.10

0.000

2.56

1.42–4.63

0.002

Lymph node involvement

 0

1

 

1

 

 1

2.01

1.19–3.42

0.009

1.27

0.54–2.97

0.581

 2

5.63

3.22–9.86

0.000

5.26

2.44–11.3

0.000

 3

12.1

6.74–21.7

0.000

12.5

5.61–27.7

0.000

Histotype

 NST - CDI

1

 

1

 

 CLI

0.75

0.44–1.26

0.275

1.03

0.52–2.06

0.925

 Other

0.59

0.30–1.15

0.122

0.40

0.12–1.32

0.132

Hystological grade

 1

1

 

1

 

 2

2.53

1.35–4.74

0.004

3.34

1.12–9.94

0.030

 3

4.31

2.30–8.05

0.000

7.52

2.61–21.7

<0.001

Tumor Size > 15 mm

4.98

2.46–10.1

0.000

5.42

1.90–15.4

0.002

Vascular invasion

5.16

2.99–8.90

0.000

3.84

1.86–7.93

0.000

ER Positive

0.44

0.28–0.69

0.000

0.34

0.18–0.64

0.001

PGR > 20%

0.63

0.41–0.97

0.034

0.37

0.19–0.69

0.002

Ki67 ≥ 20%

3.10

1.96–4.92

0.000

4.15

1.99–8.64

0.000

FOXA1 Positive

0.54

0.32–0.90

0.019

0.43

0.21–0.88

0.022

AR positive

0.60

0.40–0.91

0.015

0.38

0.21–0.70

0.002

HER2 Positive

2.50

1.25–5.00

0.010

1.98

0.70–5.58

0.195

  1. Clinical and pathological data correlated with disease free interval (DFI) and disease specific survival (DSS)