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Fig. 3 | BMC Cancer

Fig. 3

From: Docetaxel facilitates lymphatic-tumor crosstalk to promote lymphangiogenesis and cancer progression

Fig. 3

Lymphatic endothelial cells diminish cancer cell response to docetaxel. a Cancer cell death (% dead cells of total) of MDA-MB-231 cells in 3D microenvironment system +/− docetaxel treatment (10 μM) +/− LECs as measured by live/dead stain in flow cytometry. b Cancer cell death (% dead cells of total) of HCC38 cells in 3D microenvironment system +/- docetaxel treatment (10 μM) +/− LECs. c Cancer cell death (% dead cells of total) of HCC1806 cells in 3D microenvironment system +/- docetaxel treatment (10 μM) +/− LECs. d LEC-conditioned media (LEC CM) was administered to MDA-MB-231, HCC38, or HCC1806 cells followed by 1 μM docetaxel and viability assessed by CCK8 analysis. Results displayed as measured absorbance. *p < 0.05, **p < 0.01, ***p < 0.001

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