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Fig. 3 | BMC Cancer

Fig. 3

From: Gene promoter and exon DNA methylation changes in colon cancer development – mRNA expression and tumor mutation alterations

Fig. 3

Inverse promoter DNA methylation and mRNA expression alterations of APC and CTNNB1 genes in CRC and adenoma samples. a Significant DMRs in promoter regions of APC and CTNNB1 genes in CRC and adenoma samples (p < 0.05). Hypermethylation is marked with red, while hypomethylated DMRs are green. The names of the DMRs indicate the official gene symbol_number of the chromosome_start position of the DMR. CRC = colorectal cancer, NAT = normal adjacent tissue. b mRNA expression pattern of APC and CTNNB1 genes in CRC and adenoma (GSE37364 [28]). Overexpression is marked with red, while downregulated genes are green. CRC = colorectal cancer

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BMC Cancer

ISSN: 1471-2407

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