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Table 2 Dosing, dose reductions and sequencing of nal-IRI + 5-FU/LV

From: Nanoliposomal irinotecan with fluorouracil for the treatment of advanced pancreatic cancer, a single institution experience

  N = 56 (%)
Starting nal-IRI dose (mg/m2)
  < 50 23 (41)
 55 9 (16)
 60 7 (13)
 70 17 (30)
Dose reductions (#)
 0 38 (68)
 1 15 (27)
 2 3 (5)
Treatment sequencing
 FOLF (IRIN) OX ← → (nab-P) + Gem → nal-IRI + 5-FU/LV 26 (46)
 nab-P + Gem → nal-IRI + 5-FU/LV 25 (45)
 nab-P + Gem → Gem/Cap → nal-IRI + 5-FU/LV 3 (5)
 other 2 (4)