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Fig. 2 | BMC Cancer

Fig. 2

From: MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma

Fig. 2

High MAFb expression is associated with resistance to PIs. SACHI (a), H929 (b), EJM (c), XG2 (d), L363 (e), and OPM-2 (f) cells were seeded at 2 × 10^4 per well in 96-well plates in the presence of indicated concentrations of Bzb or CFZ for 48 h. Cell survival was measured by MTT Assay. Results are presented as mean ± SE (n = 4). Data are representative of 3 separate experiments. HMCLs were treated with serial concentrations of Bzb (G) and CFZ (H) for 48 h and cell viability was measured by MTT assay. The IC50 of Bzb (G) and CFZ (H) were classified based on MAFb protein (+) or (−)

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