Fig. 7

Immunolocalization of sulfated domains of HS chains using anti-HS 10E4 in colon mucosa and adenocarcinomas. a, Normal mucosa showing varying positive cytoplasmic (mostly perinuclear) and nuclear staining in both absorptive and goblet cells. (b, c), Colon adenocarcinomas showing variable degrees of highly sulfated domains of HS chains. A predominance of nuclear staining was noted, varying in degree of intensity from moderate (b) to negative or focally weak nuclear staining (c). Magnification 40X