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Fig. 6 | BMC Cancer

Fig. 6

From: Heparan sulfate proteoglycans undergo differential expression alterations in left sided colorectal cancer, depending on their metastatic character

Fig. 6

Immunolocalization of enzymes involved in the modification of HS chains. a-b Immunolocalization of N-deacetylase/N-sulfotransferase-1. a, Normal mucosa showing positive weak staining mainly in crypts (arrow) and in the extracellular matrix (asterisk). b, Metastatic tumor showing a decrease in staining in both locations; magnification 40X. c-d, Immunolocalization of HS 2-O-sulfotransferase. c, Normal mucosa showing faint staining in the crypts, with a vesicular punctate pattern (arrow), and in some basal cells, no marking in the matrix (d), Non-metastatic LSCRCs with a slightly higher immunoreaction; magnification 40X

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BMC Cancer

ISSN: 1471-2407

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