Fig. 10From: Heparan sulfate proteoglycans undergo differential expression alterations in left sided colorectal cancer, depending on their metastatic characterImmunolocalization of CS. a, Normal mucosa showing preferential staining in the stroma. b, Non-metastatic tumor, showing increased labelling, associated with the fibrous elements of the matrix, and also appearing on the crests with spotted staining in the cytoplasm (arrow). c, Metastatic tumor, in which the immunostaining is greater in all regions, and can also be observed in the cytoplasm of crypt cells (arrows). Magnification 40XBack to article page