Characteristics | Subgroups | Derivation group (n = 1506) | Validation group (n = 1506) | ||||
---|---|---|---|---|---|---|---|
AI | THR | LHR | AI | THR | LHR | ||
Overall | Unadjusted | 1.28, 1.22–1.35, < 0.001 | 1.19, 1,14–1.24, < 0.001 | 1.24, 1.19–1.30, < 0.001 | 1.32, 1.23–1.41, < 0.001 | 1.21, 1.13–1.29, < 0.001 | 1.29, 1.21–1.38, < 0.001 |
Overall | Adjusted | 1.20, 1.13–1.26, < 0.001 | 1.17, 1.11–1.24, < 0.001 | 1.19, 1.13–1.25, < 0.001 | 1.27, 1.17–1.37, < 0.001 | 1.16, 1.08–1.24, < 0.001 | 1.24, 1.15–1.35, < 0.001 |
Gender | Male | 1.27, 1.17–1.38, < 0.001 | 1.18, 1.11–1.26, < 0.001 | 1.25, 1.15–1.36, < 0.001 | 1.30, 1.18–1.43, < 0.001 | 1.17, 1.08–1.27, < 0.001 | 1.26, 1.16–1.38, < 0.001 |
Female | 1.16, 1.06–1.26, 0.001 | 1.17, 1.03–1.33, 0.019 | 1.19, 1.10–1.29, < 0.001 | 1.26, 1.06–1.48, 0.012 | 1.12, 0.97–1.29, 0.136 | 1.17, 0.96–1.42, 0.118 | |
Smoking | Ever | 1.15, 0.90–1.47, 0.133 | 1.14, 1.05–1.24, 0.011 | 1.14, 0.90–1.45, 0.270 | 1.08, 0.90–1.31, 0.397 | 1.04, 0.87–1.24, 0.649 | 1.09, 0.90–1.31, 0.381 |
Never | 1.22, 1.13–1.32, < 0.001 | 1.18, 1.07–1.29, < 0.001 | 1.23, 1.15–1.34, < 0.001 | 1.29, 1.18–1.42, < 0.001 | 1.18, 1.10–1.27, < 0.001 | 1.29, 1.18–1.40, < 0.001 | |
TNM stage | I-II | 1.59, 1.34–1.87, < 0.001 | 1.29, 1.17–1.42, < 0.001 | 1.67, 1.38–2.01, < 0.001 | 1.38, 1.12–1.69, 0.002 | 1.17, 0.84–1.62, 0.351 | 1.34, 1.09–1.65, 0.005 |
III-IV | 1.19, 1.13–1.27, < 0.001 | 1.18, 1.11–1.26, < 0.001 | 1.17, 1.10–1.23, < 0.001 | 1.26, 1.16–1.37, < 0.001 | 1.18, 1.09–1.27, < 0.001 | 1.24, 1.14–1.35, < 0.001 | |
Lauren’s classification | Intestinal type | 1.36, 1.18–1.57, < 0.001 | 1.27. 1.12–1.44, < 0.001 | 1.29, 1.11–1.51, 0.001 | 1.42, 1.20–1.66, < 0.001 | 1.21, 1.11–1.32, < 0.001 | 1.34, 1.14–1.58, < 0.001 |
Diffuse type | 1.19, 1.12–1.27, < 0.001 | 1.16, 1.07–1.26, < 0.001 | 1.17, 1.10–1.24, 0.001 | 1.13, 1.04–1.22, 0.003 | 1.12, 1.05–1.23, 0.003 | 1.16, 1.06–1.27, 0.001 | |
Tumor embolus | Positive | 1.23, 1.13–1.35, < 0.001 | 1.23, 1.14–1.33, < 0.001 | 1.28, 1.15–1.42, < 0.001 | 1.29, 1.15–1.44, < 0.001 | 1.16, 1.04–1.28, 0.006 | 1.27, 1.13–1.43, < 0.001 |
Negative | 1.17, 1.09–1.26, < 0.001 | 1.11, 1.03–1.21, 0.011 | 1.16, 1.08–1.23, < 0.001 | 1.25, 1.12–1.40, < 0.001 | 1.16, 1.06–1.28, 0.002 | 1.22, 1.09–1.37, 0.001 | |
Obesity | With | 1.11, 1.04–1.19, 0.031 | 1.13, 1.03–1.24, 0.012 | 1.09, 1.00–1.19, 0.051 | 1.12, 1.01–1.22, 0.042 | 1.07, 0.95–1.20, 0.276 | 1.07, 0.91–1.26, 0.399 |
Without | 1.26, 1.10–1.43, 0.001 | 1.18, 1.10–1.26, < 0.001 | 1.24, 1.09–1.40, 0.001 | 1.31, 1.20–1.43, < 0.001 | 1.21, 1.11–1.32, < 0.001 | 1.30, 1.18–1.42, < 0.001 | |
Hypertension | With | 1.07, 0.94–1.22, 0.338 | 1.05, 0.92–1.19, 0.502 | 1.08, 0.94–1.24, 0.271 | 1.17, 1.01–1.35, 0.037 | 1.14, 1.00–1.29, 0.045 | 1.15, 0.98–1.35, 0.096 |
Without | 1.22, 1.15–1.30, < 0.001 | 1.21, 1.14–1.28, < 0.001 | 1.21, 1.14–1.28, < 0.001 | 1.30, 1.18–1.42, < 0.001 | 1.16, 1.07–1.26, 0.001 | 1.27, 1.16–1.39, < 0.001 | |
Diabetes | With | 1.13, 1.04–1.22, 0.004 | 1.08, 1.02–1.16, 0.013 | 1.14, 1.05–1.25, 0.001 | 1.17, 1.08–1.28, 0.002 | 1.07, 0.98–1.16, 0.106 | 1.18, 1.08–1.29, < 0.001 |
Without | 1.18, 1.07–1.29, 0.001 | 1.16, 0.98–1.36, 0.080 | 1.15, 1.06–1.26, 0.001 | 1.21, 1.08–1.36, < 0.001 | 1.20, 1.05–1.38, 0.010 | 1.20, 1.09–1.30, < 0.001 |