Table 5 Multivariable Cox regression analysis of disease-specific survival for colorectal cancer patients
From: Serum MMP-8 and TIMP-1 predict prognosis in colorectal cancer
Hazard ratio | 95% CI | P-value | |
|---|---|---|---|
Age, years | |||
< =65 | 1.00 | ||
> 65 | 1.86 | 1.14–3.03 | 0.013 |
Dukes classification | |||
A | 1.00 | ||
B | 1.87 | 0.504–6.93 | 0.350 |
C | 8.63 | 2.64–28.2 | < 0.001 |
D | 15.1 | 4.43–51.6 | < 0.001 |
MMP-8/TIMP-1 ratio | |||
Low | 1.00 | ||
High | 1.72 | 0.979–3.02 | 0.059 |
MMP-9/TIMP-1 ratio | |||
Low | 1.00 | ||
High | 0.573 | 0.335–0.980 | 0.042 |