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Table 2 Median serum concentrations of MMP-8, MMP-9, TIMP-1, and molar ratios of MMPs and TIMP-1 in 335 colorectal cancer and 47 control patients

From: Serum MMP-8 and TIMP-1 predict prognosis in colorectal cancer

  Colorectal cancer Controls
Median IQR Median IQR P-valuea
MMP-8 (ng/ml) 60 33–118 68 39–107 0.358
MMP-9 (ng/ml) 192 123–273 159 60–252 0.216
TIMP-1 (ng/ml) 151 131–180 139 125–161 0.037
MMP-8/TIMP-1 (molar ratio) 0.158 0.094–0.314 0.208 0.130–0.345 0.109
MMP-9/TIMP-1 (molar ratio) 0.368 0.216–0.539 0.343 0.139–0.610 0.755
CRP (mg/l) 4.85 1.92–15.6 1.21 0.404–4.14 < 0.001
  1. Abbreviations: MMP matrix metalloproteinase, TIMP-1 tissue inhibitor of metalloproteinases-1, CRP C-reactive protein, IQR interquartile range
  2. aMann-Whitney U-test