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Fig. 5 | BMC Cancer

Fig. 5

From: Dual effects of the Nrf2 inhibitor for inhibition of hepatitis C virus and hepatic cancer cells

Fig. 5

Venn-diagram of genes down-regulated and up-regulated by brusatol or by the siRNA against Nrf2. a-b Venn-diagrams of affected genes based on the transcriptome of the HPI cells treated with brusatol or with siRNA against Nrf2. The microarray data were deposited in Gene Expression Omnibus (accession numbers: GSE52321 and GSE98920). a The numbers of genes down-regulated (< 0.5-fold vs. control) by the siRNA or by brusatol are shown in the circles. The number of genes commonly down-regulated is shown in the overlapped region of the circles. The number of genes down-regulated exclusively by each agent is shown in the non-overlapped region; b The numbers of genes up-regulated (> 0.5-fold vs. control) by the siRNA or by brusatol are shown in the circles. The number of genes commonly up-regulated is shown in the overlapped region of the circles. The number of genes up-regulated exclusively by each reagent is shown in the non-overlapped region

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