Thoracic injection of low-dose interleukin-2 as an adjuvant therapy improves the control of the malignant pleural effusions: a systematic review and meta-analysis base on Chinese patients

Han, Liping; Jiang, Qiufang; Yao, Wei; Fu, Tian; Zeng, Qingdi

doi:10.1186/s12885-018-4581-5

Table 3 Design quality of included trials

From: Thoracic injection of low-dose interleukin-2 as an adjuvant therapy improves the control of the malignant pleural effusions: a systematic review and meta-analysis base on Chinese patients

Study	Region	Sequence generation	Allocation concealment	Blind	Outcome data	Selective outcome reporting	Other sources of bias	ITT	Risk of bias
Changjie H 2001 [15]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Xiuzhi Y 2001 [16]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Zhuo S 2004 [17]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Junyan W 2005 [18]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Haiying X 2009 [19]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Xiaoxia H 2009 [20]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Lizheng C 2009 [21]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Jinguang C 2009 [22]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Junfeng W 2010 [23]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Jingping Z 2010 [24]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Cheng X 2010 [25]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Fang S 2011 [26]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Xueling L 2011 [27]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Yan Q 2011 [28]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Li J 2013 [29]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Lijie H 2014 [30]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Miao H 2016 [31]	Single center	Random number table	Unclear	Unclear	Yes	No	Unclear	Yes	Unclear risk of bias
Baohua Y 2017 [32]	Single center	Random number table	Unclear	Clear	Yes	No	Clear	Yes	Low risk of bias

ITT intention-to-treat

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ISSN: 1471-2407

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