Table 1 Percent of samples with mutated COMPASS complex proteins (COSMIC v83)
From: WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage
Frequency of Mutations in Colon Adenocarcinoma | ||
|---|---|---|
Gene | Percent Mutated | Samples (Mutated/Tested) |
KMT2C/MLL3 | 13% | 323/2478 |
KMT2D/MLL2 | 11% | 243/2209 |
KMT2A/MLL | 7% | 152/2178 |
KMT2B/MLL4 | 7% | 150/2130 |
KMT2F/SETD1A | 6% | 116/2109 |
KMT2G/SETD1B | 3% | 67/2098 |
RBBP5 | 2% | 32/2109 |
WDR5 | 1% | 28/2109 |
ASH2L | 1% | 25/2109 |
DPY30 | < 1% | 6/2098 |