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Table 4 IC50 values calculated by Calcusyn for single chemotherapy or chemotherapy in combination with DEAB tested on HT-29/eGFP cancer cells

From: ALDH1A inhibition sensitizes colon cancer cells to chemotherapy

 

IC50 (μg/ml)

CisPt

0.36 (r = 0.985)

CisPt + DEAB (20 μg/ml)

0.22 (r = 0.993)

RAL

0.69 (r = 0.849)

RAL + DEAB (20 μg/ml)

0.37 (r = 0.977)

5-FU

0.38 (r = 0.844)

5-FU + DEAB (20 μg/ml)

0.003 (r = 0.508)

IRI

3.26 (r = 0.882)

IRI + DEAB (20 μg/ml)

0.003 (r = 0.750)

  1. The results are from two or three independent experiments measured in quadruplicates