Table 3 IC50 values calculated by Calcusyn for 3 CRC cell lines treated by selected chemotherapeutic agents
From: ALDH1A inhibition sensitizes colon cancer cells to chemotherapy
Chemotherapeutic agent | CRC cell line | IC50 value (μg/ml) |
|---|---|---|
CAP [μg/ml] | HCT-116/eGFP | 296.13 (r = 0.993) |
HT-29/eGFP | 309.50 (r = 0.921) | |
LS-180/eGFP | 267.86 (r = 0.952) | |
RAL [μg/ml] | HCT-116/eGFP | 2.5 (r = 0.866) |
HT-29/eGFP | 0.69 (r = 0.849) | |
LS-180/eGFP | 3.48 (r = 0.916) | |
5-FU [μg/ml] | HCT-116/eGFP | 0.48 (r = 0.959) |
HT-29/eGFP | 0.38 (r = 0.844) | |
LS-180/eGFP | 0.27 (r = 0.992) | |
IRI [μg/ml] | HCT-116/eGFP | 1.30 (r = 0.989) |
HT-29/eGFP | 3.26 (r = 0.882) | |
LS-180/eGFP | 0.37 (r = 0.943) |