PD-L1 assessment in pediatric rhabdomyosarcoma: a pilot study

Bertolini, Giulia; Bergamaschi, Luca; Ferrari, Andrea; Renne, Salvatore L.; Collini, Paola; Gardelli, Cecilia; Barisella, Marta; Centonze, Giovanni; Chiaravalli, Stefano; Paolino, Cinzia; Milione, Massimo; Massimino, Maura; Casanova, Michela; Gasparini, Patrizia

doi:10.1186/s12885-018-4554-8

BMC Cancer

Table 1 PD-L1 expression

From: PD-L1 assessment in pediatric rhabdomyosarcoma: a pilot study

ID	Histotype	Fusion Trascript	PD-L1 IHC				Comments	Status	T	N	M	IRS	Outcome
			TC score		IC score
			Clone SP142	Clone 22C3	Clone SP142	Clone 22C3
RMS1	ERMS	negative	0	0	2	2	IC only outside tumor	In therapy	T2B	N0	M1	4	DOD
RMS2	ARMS	PAX7-FOXO1	0	0	0	0		Pre-treated	T1	N0	M0	1	DOD
RMS3	ERMS	negative	0	0	0	0		In therapy	T2B	N0	M1	4	DOD
RMS4	ARMS	negative	0	0	0	0		At diagnosis	T2B	N0	M1	4	DOD
RMS5	ERMS	negative	0	0	0	0		At diagnosis	T2A	N0	M1	4	1°RC
RMS6	ARMS	negative	0	0	3	3	IC outside and infiltrating tumor	At diagnosis	T2A	N1	M1	4	DOD
RMS7	ARMS	PAX3-FOXO1	0	0	1	1	Few cells in IC outside and infiltrating tumor	At diagnosis	T1A	N0	M1	4	DOD
RMS8	ERMS	negative	0	0	2	2	IC only outside tumor	Pre-treated	T2B	N0	M0	3	1°RC
RMS9	ERMS	negative	0	0	3	3	IC outside and infiltrating tumor	At diagnosis	T2B	N0	M0	3	1°RC
RMS10	ARMS	negative	0	0	2	2	IC only outside tumor	Pre-treated	T2B	N0	M0	3	2°RC
RMS11	RMS	negative	0	0	0	0		At diagnosis	T2B	N1	M0	3	DOD
RMS12	ARMS	PAX7-FOXO1	0	0	2	2	IC only outside tumor	At diagnosis	T2B	N1	M0	3	1°RC
RMS13	ARMS	PAX7-FOXO1	0	0	3	3	IC outside and infiltrating tumor	Pre-treated	T2A	N0	M1	3	DOD
RMS14	ARMS	PAX3-FOXO1	0	0	0	0		At diagnosis	T1A	N0	M1	4	DOD
RMS15	ERMS	negative	0	0	2	2	IC only infiltrating tumor	At diagnosis	T1A	N0	M0	3	1°RC
RMS16	ARMS	PAX3-FOXO1	0	0	3	3	IC outside and infiltrating tumor	At diagnosis	T2B	N1	M0	3	1°RC
RMS17	ARMS	PAX3-FOXO1	0	0	0	0		At diagnosis	T2B	N1	M1	4	DOD
RMS18	ERMS	negative	0	0	0	0		At diagnosis	T2B	N0	M0	3	1°RC
RMS19	ERMS	negative	0	0	2	2	IC outside and infiltrating tumor	post-treatment	T2B	N0	M0	3	1°RC
RMS20	ARMS	negative	0	0	0	0		post treated	T1A	N0	M0	3	1°RC
RMS21	ERMS	negative	0	0	2	2	IC outside and infiltrating tumor	post-treatment	T2B	N1	M0	3	DOD
RMS22	ERMS	negative	0	0	2	2	IC outside and infiltrating tumor	At diagnosis	T2B	N0	M0	3	1°RC
RMS23	ERMS	negative	0	0	3	3	IC outside and infiltrating tumor	post-treatment	T2B	N0	M0	3	1°RC
RMS24	ERMS	negative	0	0	0	0		At diagnosis	T2B	N0	M0	3	1°RC
RMS25	ERMS	negative	0	0	2	2	IC outside and infiltrating tumor	post-treatment	T2B	N0	M0	3	1°RC

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ISSN: 1471-2407

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