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Table 5 FPRP values for associations between HCC risk and block 3 haplotype frequencies (AG vs. AA+GG)

From: A rare CHD5 haplotype and its interactions with environmental factors predicting hepatocellular carcinoma risk

Variables

Statistical powera

Prior probability

0.1

0.01

0.001

0.0001

HCC risk in >55 years old group

 Discovery study

0.704

0.216

0.493

0.721

0.885

 Replication study

0.689

0.017

0.271

0.525

0.843

 Combined study

0.837

0.004

0.010

0.347

0.706

HCC risk in drinking group

 Discovery study

0.792

0.003

0.013

0.298

0.635

 Replication study

0.658

0.005

0.017

0.424

0.757

 Combined study

1

< 0.001

0.005

0.069

0.236

  1. Block 3, rs12564469 and rs9434711
  2. If the prior probability <0.20, the results in FPRP are in bold