| |
Allelesa
|
Case, Control Ratio Countsb
|
Case, Control Frequenciesc
|
Chi square
|
PARd
|
P
adjusted
e
|
P
permutation
f
|
|---|
|
Replication
|
|
rs12564469
|
A > G
|
659:289, 570:298
|
0.695, 0.657
|
3.065
|
0.0800
|
0.1029
|
0.1062
|
|
rs9434711
|
A > G
|
341:629, 309:579
|
0.352, 0.348
|
0.026
|
0.8718
|
0.8485
|
0.9601
|
|
Combined
|
|
rs12564469
|
A > G
|
1003:431, 857:445
|
0.699, 0.658
|
5.328
|
0.0210
|
0.0290
|
0.0286
|
|
rs9434711
|
A > G
|
511:953, 460:868
|
0.349, 0.346
|
0.022
|
0.8829
|
0.9137
|
0.9704
|
- aThe major allele is listed first, then the minor allele
- bNumber of alleles were compared in cases versus controls: allele(1):allele(2) cases, allele(1):allele(2) controls
- cFrequency of the association allele
- dPAR, population attributable risk
- eCalculated in logistical regression models with adjustment for age, gender, smoking and drinking status
- fP for 105 permutation test
