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Table 4 Genes contributing to the upregulated oxidative phosphorylation pathway and the downregulated TNFA signaling through NFKB pathway in PRA transgenics and LumA/LumB subtypes

From: Gene expression profile and cancer-associated pathways linked to progesterone receptor isoform a (PRA) predominance in transgenic mouse mammary glands

Gene symbol

FC

P-value

TIMM9

1.8

0.019

PDHB

1.4

0.024

IL7R

−4.6

0.036

KYNU

−3.1

0.006

EGR3

−2.9

0.029

EGR1

−2.9

0.037

MSC

−2.4

0.022

LAMB3

−2.3

0.001

BMP2

−2.0

0.019

PDE4B

−2.0

0.018

NR4A1

−1.9

0.032

FOSB

−1.9

0.011

KLF2

−1.8

0.041

PMEPA1

−1.8

0.043

JUNB

−1.6

0.009

CD44

−1.6

0.035

CCL2

−1.5

0.001

IER2

−1.5

0.047

ZFP36

−1.5

0.029

  1. P-value and fold change (FC) of PRA/wild-type comparison