Table 3 Significantly up and downregulated hallmark pathways for breast cancer subtypes and statistical significance of the overlap with those found for PRA transgenics
Number of significant pathways in the set (out of 50 total) | Number of overlapping pathways | P value | ||
|---|---|---|---|---|
Upregulated | PRA Transgenic | 8 | ||
Luminal A | 10 | 3 | 0.188 | |
Luminal B | 15 | 5 | 0.043 | |
Downregulated | PRA Transgenic | 19 | ||
Luminal A | 28 | 16 | 0.002 | |
Luminal B | 24 | 15 | 7.10E-04 | |