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Table 2 Association between PSCA staining and prostate cancer phenotype

From: PSCA expression is associated with favorable tumor features and reduced PSA recurrence in operated prostate cancer

  Evaluable PSCA staining (%)  
Parameter (N) Negative Weak Moderate Strong P
Total 9642 46.3 22.4 24.5 6.8  
Tumor stage
 pT2 6003 41.5 23.6 26.9 8.0 < 0.0001
 pT3a 2269 51.1 20.9 22.5 5.5
 pT3b-pT4 1326 59.7 19.5 17.0 3.8
Gleason grade
 ≤3 + 3 1713 47.0 23.0 22.8 7.2 < 0.0001
 3 + 4 5275 43.4 22.8 26.5 7.4
 3 + 4 Tertiary 5 441 46.3 23.6 23.8 6.3
 4 + 3 977 50.2 21.2 21.8 6.9
 4 + 3 Tertiary 5 666 48.6 22.8 23.7 4.8
 ≥4 + 4 562 61.6 17.4 17.8 3.2
Lymph node metastasis
 N0 5873 46.0 22.4 24.4 7.2 < 0.0001
 N+ 674 59.9 19.1 17.7 3.3
Preoperative PSA level (ng/ml)
 < 4 1099 48.6 19.7 25.3 6.4 0.0118
 4–10 5715 44.9 23.4 24.7 7.0
 10–20 1995 46.9 21.8 24.1 7.3
 > 20 724 51.2 20.0 23.6 5.1
Surgical margin
 Negative 7544 45.1 22.8 24.8 7.3 < 0.0001
 Positive 1882 51.3 20.8 22.6 5.3