Table 1 Selection criteria

Families with three or more second degree relatives with breast cancer or ovarian cancer, at least two of which must be first degree.

 1) Three or more family members with breast and/or ovarian cancer.

 (Br: Only breast cancer. Ov: at least one ovarian cancer).

Families with two first degree relatives with breast cancer or ovarian cancer.

 2) Two family members with ovarian cancer.

 3) One family member with ovarian cancer and one with breast cancer.

 4) One family member with a male breast cancer and one with breast and/or ovarian cancer.

 5) Two family members with breast cancer before the age of 50.

 6) One family member with bilateral breast cancer and one with breast cancer, at least one before the age of 50.

Families with a single case with breast cancer or ovarian cancer.

 7) Single affected individual with breast or ovarian cancer diagnosed before the age of 30.

 8) Single affected individual with breast and ovarian cancer.

 9) Single affected individual with bilateral breast cancer, first diagnosed before the age of 40.