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Table 1 LC3B expressions and clinicopathologic variables in oropharyngeal and oral cavity SCC patients

From: Differences in LC3B expression and prognostic implications in oropharyngeal and oral cavity squamous cell carcinoma patients

  Oropharyngeal SCC Oral Cavity SCC
  Total Low LC3B High LC3B P value Total Low LC3B High LC3B P value
Total 47 26 (55%) 21 (45%) < 0.0001 95 67 (71%) 28 (29%) < 0.0001
Age 41–83 (60) 43–83 (59) 41–80 (62) 0.46 28–97 (60) 28–97 (62) 34–83 (58) 0.21
 ≤ 60 years 27 18 (69%) 9 (43%) 0.07 50 33 (49%) 17 (61%) 0.31
 >  60 years 20 8 (31%) 12 (57%)   45 34 (51%) 11 (39%)  
Gender
 Male 36 19 (73%) 17 (81%) 0.53 60 41 (61%) 19 (68%) 0.54
 Female 11 7 (27%) 4 (19%)   35 26 (39%) 9 (32%)  
Tumour stage
 1 & 2 26 18 (69%) 8 (38%) 0.6 67 46 (69%) 21 (75%) 0.54
 3 & 4 21 8 (31%) 13 (62%)   28 21 (31%) 7 (25%)  
Nodal stage
 0 & 1 22 11 (42%) 11 (52%) 0.49 71 53 (79%) 18 (64%) 0.13
 2 & 3 25 15 (58%) 10 (48%)   24 14 (21%) 10 (36%)  
TNM stage
 I & II 10 6 (23%) 4 (19%) 0.74 47 34 (51%) 13 (46%) 0.7
 III & IV 37 20 (77%) 17 (81%)   48 33 (49%) 15 (54%)  
Tumour grade missing = 3     missing = 2    
 1 & 2 28 15 (60%) 13 (68%) 0.57 75 55 (85%) 20 (71%) 0.14
 3 16 10 (40%) 6 (32%)   18 10 (15%) 8 (29%)  
Recurrence
 Absent 30 18 (69%) 12 (57%) 0.39 61 48 (72%) 13 (46%) 0.02*
 Present 17 8 (31%) 9 (43%)   34 19 (28%) 15 (54%)  
Smoking status missing = 2     missing = 9    
 Never-smoker 3 2 (67%) 1 (33%) 1.00a 20 15 (75%) 5 (25%) 0.78a
 Ex & current smoker 42 23 (55%) 19 (45%)   66 46 (70%) 20 (30%)  
  1. a= Fisher’s exact test is performed due to one of the cell frequency is less than or equals to 5
  2. *= statistical significance (p < 0.05)