| Oropharyngeal SCC | Oral Cavity SCC | ||||||
---|---|---|---|---|---|---|---|---|
 | Total | Low LC3B | High LC3B | P value | Total | Low LC3B | High LC3B | P value |
Total | 47 | 26 (55%) | 21 (45%) | < 0.0001 | 95 | 67 (71%) | 28 (29%) | < 0.0001 |
Age | 41–83 (60) | 43–83 (59) | 41–80 (62) | 0.46 | 28–97 (60) | 28–97 (62) | 34–83 (58) | 0.21 |
 ≤ 60 years | 27 | 18 (69%) | 9 (43%) | 0.07 | 50 | 33 (49%) | 17 (61%) | 0.31 |
 >  60 years | 20 | 8 (31%) | 12 (57%) |  | 45 | 34 (51%) | 11 (39%) |  |
Gender | ||||||||
 Male | 36 | 19 (73%) | 17 (81%) | 0.53 | 60 | 41 (61%) | 19 (68%) | 0.54 |
 Female | 11 | 7 (27%) | 4 (19%) |  | 35 | 26 (39%) | 9 (32%) |  |
Tumour stage | ||||||||
 1 & 2 | 26 | 18 (69%) | 8 (38%) | 0.6 | 67 | 46 (69%) | 21 (75%) | 0.54 |
 3 & 4 | 21 | 8 (31%) | 13 (62%) |  | 28 | 21 (31%) | 7 (25%) |  |
Nodal stage | ||||||||
 0 & 1 | 22 | 11 (42%) | 11 (52%) | 0.49 | 71 | 53 (79%) | 18 (64%) | 0.13 |
 2 & 3 | 25 | 15 (58%) | 10 (48%) |  | 24 | 14 (21%) | 10 (36%) |  |
TNM stage | ||||||||
 I & II | 10 | 6 (23%) | 4 (19%) | 0.74 | 47 | 34 (51%) | 13 (46%) | 0.7 |
 III & IV | 37 | 20 (77%) | 17 (81%) |  | 48 | 33 (49%) | 15 (54%) |  |
Tumour grade | missing = 3 |  |  |  | missing = 2 |  |  |  |
 1 & 2 | 28 | 15 (60%) | 13 (68%) | 0.57 | 75 | 55 (85%) | 20 (71%) | 0.14 |
 3 | 16 | 10 (40%) | 6 (32%) |  | 18 | 10 (15%) | 8 (29%) |  |
Recurrence | ||||||||
 Absent | 30 | 18 (69%) | 12 (57%) | 0.39 | 61 | 48 (72%) | 13 (46%) | 0.02* |
 Present | 17 | 8 (31%) | 9 (43%) |  | 34 | 19 (28%) | 15 (54%) |  |
Smoking status | missing = 2 |  |  |  | missing = 9 |  |  |  |
 Never-smoker | 3 | 2 (67%) | 1 (33%) | 1.00a | 20 | 15 (75%) | 5 (25%) | 0.78a |
 Ex & current smoker | 42 | 23 (55%) | 19 (45%) |  | 66 | 46 (70%) | 20 (30%) |  |