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Table 1 LC3B expressions and clinicopathologic variables in oropharyngeal and oral cavity SCC patients

From: Differences in LC3B expression and prognostic implications in oropharyngeal and oral cavity squamous cell carcinoma patients

 

Oropharyngeal SCC

Oral Cavity SCC

 

Total

Low LC3B

High LC3B

P value

Total

Low LC3B

High LC3B

P value

Total

47

26 (55%)

21 (45%)

< 0.0001

95

67 (71%)

28 (29%)

< 0.0001

Age

41–83 (60)

43–83 (59)

41–80 (62)

0.46

28–97 (60)

28–97 (62)

34–83 (58)

0.21

 ≤ 60 years

27

18 (69%)

9 (43%)

0.07

50

33 (49%)

17 (61%)

0.31

 >  60 years

20

8 (31%)

12 (57%)

 

45

34 (51%)

11 (39%)

 

Gender

 Male

36

19 (73%)

17 (81%)

0.53

60

41 (61%)

19 (68%)

0.54

 Female

11

7 (27%)

4 (19%)

 

35

26 (39%)

9 (32%)

 

Tumour stage

 1 & 2

26

18 (69%)

8 (38%)

0.6

67

46 (69%)

21 (75%)

0.54

 3 & 4

21

8 (31%)

13 (62%)

 

28

21 (31%)

7 (25%)

 

Nodal stage

 0 & 1

22

11 (42%)

11 (52%)

0.49

71

53 (79%)

18 (64%)

0.13

 2 & 3

25

15 (58%)

10 (48%)

 

24

14 (21%)

10 (36%)

 

TNM stage

 I & II

10

6 (23%)

4 (19%)

0.74

47

34 (51%)

13 (46%)

0.7

 III & IV

37

20 (77%)

17 (81%)

 

48

33 (49%)

15 (54%)

 

Tumour grade

missing = 3

   

missing = 2

   

 1 & 2

28

15 (60%)

13 (68%)

0.57

75

55 (85%)

20 (71%)

0.14

 3

16

10 (40%)

6 (32%)

 

18

10 (15%)

8 (29%)

 

Recurrence

 Absent

30

18 (69%)

12 (57%)

0.39

61

48 (72%)

13 (46%)

0.02*

 Present

17

8 (31%)

9 (43%)

 

34

19 (28%)

15 (54%)

 

Smoking status

missing = 2

   

missing = 9

   

 Never-smoker

3

2 (67%)

1 (33%)

1.00a

20

15 (75%)

5 (25%)

0.78a

 Ex & current smoker

42

23 (55%)

19 (45%)

 

66

46 (70%)

20 (30%)

 
  1. a= Fisher’s exact test is performed due to one of the cell frequency is less than or equals to 5
  2. *= statistical significance (p < 0.05)