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Table 1 The clinical parameters of the patient

From: Haemophagocytic lymphohistiocytosis occurred during induction chemotherapy in an acute monocytic leukemia patient with FLT3-ITD and DNMT3A mutations

Parameters Before chemotherapy d6 during the IA chemotherapy d11–14 after finishing chemotherapy d20 after finishing chemotherapy
WBC (×109/L) 25.3 3.2 0.4 15.0
Hb (g/L) 142 66 73 78
PLT (×109/L) 11.0 5 1 42
APTT (s) 57.7 72 104 46.2
PT (s) 14.0 14.6 30.5 11.8
Fbg (g/L) 3.1 2.2 0.87 4.8
TG (mmol/L) 1.5 0.8 0.9
SF (μg/L) 688 324 > 3000 1259
PCT (ng/mL) 2.8 0.75 3.8 0.7
CRP (mg/L) 44.5 25.4 35.7 49.1
LDH (U/L) 303 481 57 392
  1. WBC white blood cell (normal range, 4-10 × 109/L), Hb hemoglobin (normal range, 120–150 g/L), PLT platelet (normal range,100–300 × 109/L), APTT activated partial prothrombin time (normal range, 21.1–36.5 s), P T prothrombin time (normal range, 9.8–12.1 s), Fbg fibrinogen (normal range, 1.8–3.5 g/L), TG triglycerides (normal range, 0–1.7 mmol/L), SF serum ferritin (normal range, 30–400 μg/L), PCT:procalcitonin (< 0.5 ng/mL), CRP C-reactive protein (normal range, 0–8 mg/L), LDH lactate dehydrogenase (normal range, 0–248 U/L), IA regimen idarubicin, 8 mg/m2/d at d1–3, Cytarabine, 100 mg/m2/d at d1–7