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Table 1 Assessment of correlation between levels of siRNA-mediated LRP knockdown and viability, apoptotic levels and caspase-3 activity of early (SW-480) and late (DLD-1) stage colorectal cancer cells, using Pearson’s correlation co-efficients (R)

From: Knock-down of LRP/LR promotes apoptosis in early and late stage colorectal carcinoma cells via caspase activation

Cell line SW-480 DLD-1
Correlation between total LRP levels before and after siRPSA #1 transfection (R-value) 0.91 0.96
Correlation between siRPSA #1-mediated LRP knockdown and reduction in cell viability (R-value) 0.99 0.98
Correlation between siRPSA #2-mediated LRP knockdown and reduction in cell viability (R-value) 0.99 0.93
Correlation between total levels of apoptosis and total LRP levels after siRPSA #1 transfection (R-value) 0.99 0.98
Correlation between increases in caspase-3 activity and total LRP levels after siRPSA #1 (R-value) 0.94 0.93