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Table 1 Characteristics of patients with primary BC, 1993–2013

From: Risk of second primary Cancer among bladder Cancer patients: a population-based cohort study in Korea

 

Total

Men

Women

 

n

%

n

%

n

%

Patients with BC

48,875

100

39,351

100

9524

100

Period of BC diagnosis

 1993–1997

6892

14.10

5592

14.21

1300

13.65

 1998–2002

10,484

21.45

8377

21.29

2107

22.12

 2003–2007

13,585

27.80

10,942

27.81

2643

27.75

 2008–2013

17,914

36.65

14,440

36.70

3474

36.48

Average age at diagnosis with BC (years; mean, SD)

65.39

12.46

64.81

12.20

67.80

13.22

Median age at diagnosis with BC (years; median, range)

67

105 (1–106)

66

100 (1–101)

70

105 (1–106)

Age at primary BC diagnosis (years)

 0–39

1608

3.29

1259

3.20

349

3.66

 40–59

12,489

25.55

10,601

26.94

1888

19.82

 ≥60

34,778

71.16

27,491

69.86

7287

76.51

Percentage of primary treatment status

 Surgery

42,448

86.85

34,653

88.06

7795

81.85

 Radiation

1298

2.66

1004

2.55

294

3.09

 Chemotherapy

6161

12.61

5045

12.82

1116

11.72

Average follow-up after BC diagnosis (years; mean, SD)

5.65

5.09

5.70

5.06

5.46

5.21

Median follow-up after BC diagnosis (years; median, range)

4.13

20.80(0–20.80)

4.21

20.80(0–20.80)

3.67

20.80(0–20.80)

Number of patients who developed a SPC

3495

7.15

3116

7.92

379

3.98

Average age at SPC diagnosis (years; mean, SD)

70.57

9.28

70.71

8.94

69.40

11.67

Median age at SPC diagnosis (years; median, range)

 

71(10–95)

 

71.5(10–95)

 

71(12–93)

Average interval between primary cancer and SPC (years; mean, SD)

5.23

4.30

5.18

4.29

5.75

4.39

Median interval between primary cancer and SPC (years; median, range)

 

4.17(0.17–0.67)

 

4.08(0.17–20.67)

 

4.75(0.17–19.08)

Number of patients by latency between primary cancer and SPC (years)

 1

556

15.91

469

12.95

47

16.19

 1–4

1409

40.31

1176

39.67

144

40.61

 5–9

1000

28.61

813

29.20

106

28.07

 ≥10

530

15.16

438

18.18

66

15.12

Number of patients by age at SPC diagnosis (years)

 0–39

13

0.37

8

0.26

5

1.32

 40–59

396

11.33

327

10.49

69

18.21

 ≥60

3086

88.30

2781

89.25

305

80.47

Average follow-up after SPC diagnosis, (years; mean, SD)

2.55

2.91

2.48

2.82

3.10

3.52

Median follow-up after SPC diagnosis (years; median, range)

1.42

20.00(0–20.00)

1.42

20.00(0–20.00)

1.67

19.50(0–19.50)

Number of subsequent primary cancers

 1

3259

6.67

2896

7.36

363

3.81

 2

217

0.44

203

0.52

14

0.15

 ≥3

19

0.04

17

0.04

2

0.02

  1. BC: bladder cancer, SD: standard deviation, SPC: second primary cancer