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Fig. 4 | BMC Cancer

Fig. 4

From: Estrogen receptor α dependent regulation of estrogen related receptor β and its role in cell cycle in breast cancer

Fig. 4

Estrogen regulates the expression of ERRβ. a Western blots and densitometry analyses showing up-regulation of ERRβ upon estrogen treatment at different concentrations [10 nM (i) & 100 nM (ii)] for different time points (0, 6, 12, 24, 48 h) in MCF7 cells. MCF7 cells showed > 2 fold high expression of ERRβ upon the treatment of 100 nM E2 treatment. b Combinatorial treatment of MCF7 cells with estrogen and tamoxifen decrease ERRβ expression. The association between normalized percentage expression in different groups were analyzed using One-way ANOVA test (ns- no significance, *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001)

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