Table 2 Adverse events associated with the first course of hepatic arterial infusion chemotherapy
No. (%) | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Total |
|---|---|---|---|---|---|
Clinical | |||||
 Nausea/Vomiting | 9 (17) | 2 (4) | 0 | 0 | 11(20) |
 Anorexia | 10 (19) | 7 (13) | 1(25) | 0 | 18 (33) |
 Fever | 5 (9) | 1 (25) | 0 | 0 | 6 (11) |
 Pain | 11 (20) | 0 | 0 | 0 | 11 (20) |
 Fatigue | 8 (15) | 1(25) | 0 | 0 | 9 (17) |
 Diarrhea | 0 | 1(25) | 0 | 0 | 1(25) |
Laboratory abnormalities | |||||
 Leucocyte count decrease | 22 (41) | 6 (11) | 1(25) | 0 | 29 (54) |
 Neutrophil count decrease | 10 (19) | 2 (4) | 0 | 0 | 12 (22) |
 Anemia | 26 (48) | 7 (13) | 2 (4) | 0 | 35 (65) |
 Platelet count decrease | 22 (41) | 9 (17) | 4 (7) | 0 | 35 (65) |
 AST/ALT increase | 24 (44) | 4 (7) | 4 (7) | 0 | 32 (59) |
 Creatinine increase | 15 (28) | 0 | 0 | 0 | 15 (28) |
Total | Â | Â | 12 (21.8) | 0 (0) | Â |