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Table 3 Phase two EBRT component dose constraints

From: PROstate Multicentre External beam radioTHErapy Using a Stereotactic boost: the PROMETHEUS study protocol

Structure Per-Protocol Minor Variation Major Variation
PTVebrt D95 > 46 Gy 44–46 Gy < 44 Gy
Prostatic Urethra PRV Dmax < 47 Gy Dmax: 47–50 Gy Dmax > 50 Gy
Small Bowel Dmax < 47 Gy Dmax: 47–50 Gy Dmax > 50 Gy
Neck of Femur Dmax < 35 Gy Dmax: 35–45 Gy Dmax> 45 Gy
Rectum V45 < 25% 25–35% > 35%
Bladder V45 < 25% 25–35% > 35%