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Fig. 5 | BMC Cancer

Fig. 5

From: IΚΚε cooperates with either MEK or non-canonical NF-kB driving growth of triple-negative breast cancer cells in different contexts

Fig. 5

p52 does not contribute to viability or invasive potential. a) Using the MDA-MB-468 cells with stably knocked down IKBKE, we transiently knocked down NFKB2 using siRNA interference. Representative western blots shown using 30 μg protein lysate collected 72 h following siRNA transfection. b) Cell viability over 72 h was not significantly altered by loss of IKKε or p52, left. Similarly, loss of IKKε or p52 had no effect on invasiveness at 72 h, right. c) Viability, left, and invasion, right, experiments were repeated using the BT549 cells stably expressing IKKε. ns, not significant according to one-way ANOVA, post hoc-Tukey

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