TY - JOUR AU - Siegel, R. AU - Naishadham, D. AU - Jemal, A. PY - 2013 DA - 2013// TI - Cancer statistics, 2013 JO - CA Cancer J Clin VL - 63 UR - https://doi.org/10.3322/caac.21166 DO - 10.3322/caac.21166 ID - Siegel2013 ER - TY - JOUR AU - Lehmann, B. D. AU - Bauer, J. A. AU - Chen, X. AU - Sanders, M. E. AU - Chakravarthy, A. B. AU - Shyr, Y. PY - 2011 DA - 2011// TI - Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies JO - J Clin Invest VL - 121 UR - https://doi.org/10.1172/JCI45014 DO - 10.1172/JCI45014 ID - Lehmann2011 ER - TY - JOUR AU - Prat, A. AU - Adamo, B. AU - Cheang, M. C. AU - Anders, C. K. AU - Carey, L. A. AU - Perou, C. M. PY - 2013 DA - 2013// TI - Molecular characterization of basal-like and non-basal-like triple-negative breast cancer JO - Oncologist VL - 18 UR - https://doi.org/10.1634/theoncologist.2012-0397 DO - 10.1634/theoncologist.2012-0397 ID - Prat2013 ER - TY - JOUR AU - Mayer, I. A. AU - Abramson, V. G. AU - Lehmann, B. D. AU - Pietenpol, J. A. PY - 2014 DA - 2014// TI - New strategies for triple-negative breast cancer--deciphering the heterogeneity JO - Clin Cancer Res VL - 20 UR - https://doi.org/10.1158/1078-0432.CCR-13-0583 DO - 10.1158/1078-0432.CCR-13-0583 ID - Mayer2014 ER - TY - JOUR AU - Ossovskaya, V. AU - Wang, Y. AU - Budoff, A. AU - Xu, Q. AU - Lituev, A. AU - Potapova, O. PY - 2011 DA - 2011// TI - Exploring molecular pathways of triple-negative breast cancer JO - Genes Cancer VL - 2 UR - https://doi.org/10.1177/1947601911432496 DO - 10.1177/1947601911432496 ID - Ossovskaya2011 ER - TY - JOUR AU - Bendinelli, P. AU - Matteucci, E. AU - Maroni, P. AU - Desiderio, M. A. PY - 2009 DA - 2009// TI - NF-kappaB activation, dependent on acetylation/deacetylation, contributes to HIF-1 activity and migration of bone metastatic breast carcinoma cells JO - Mol Cancer Res VL - 7 UR - https://doi.org/10.1158/1541-7786.MCR-08-0548 DO - 10.1158/1541-7786.MCR-08-0548 ID - Bendinelli2009 ER - TY - JOUR AU - Hoeflich, K. P. AU - O'Brien, C. AU - Boyd, Z. AU - Cavet, G. AU - Guerrero, S. AU - Jung, K. PY - 2009 DA - 2009// TI - In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models JO - Clin Cancer Res VL - 15 UR - https://doi.org/10.1158/1078-0432.CCR-09-0317 DO - 10.1158/1078-0432.CCR-09-0317 ID - Hoeflich2009 ER - TY - JOUR AU - Ibrahim, Y. H. AU - García-García, C. AU - Serra, V. AU - He, L. AU - Torres-Lockhart, K. AU - Prat, A. PY - 2012 DA - 2012// TI - PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition JO - Cancer Discov VL - 2 UR - https://doi.org/10.1158/2159-8290.CD-11-0348 DO - 10.1158/2159-8290.CD-11-0348 ID - Ibrahim2012 ER - TY - JOUR AU - Kim, H. S. AU - Yom, C. K. AU - Kim, H. J. AU - Lee, J. W. AU - Sohn, J. H. AU - Kim, J. H. PY - 2010 DA - 2010// TI - Overexpression of p53 is correlated with poor outcome in premenopausal women with breast cancer treated with tamoxifen after chemotherapy JO - Breast Cancer Res Treat VL - 121 UR - https://doi.org/10.1007/s10549-009-0560-5 DO - 10.1007/s10549-009-0560-5 ID - Kim2010 ER - TY - JOUR AU - Stemke-Hale, K. AU - Gonzalez-Angulo, A. M. AU - Lluch, A. AU - Neve, R. M. AU - Kuo, W. L. AU - Davies, M. PY - 2008 DA - 2008// TI - An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer JO - Cancer Res VL - 68 UR - https://doi.org/10.1158/0008-5472.CAN-07-6854 DO - 10.1158/0008-5472.CAN-07-6854 ID - Stemke-Hale2008 ER - TY - JOUR AU - Sen, R. AU - Baltimore, D. PY - 1986 DA - 1986// TI - Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism JO - Cell VL - 47 UR - https://doi.org/10.1016/0092-8674(86)90807-X DO - 10.1016/0092-8674(86)90807-X ID - Sen1986 ER - TY - JOUR AU - Duckett, C. S. PY - 2002 DA - 2002// TI - Apoptosis and NF-kappa B: the FADD connection JO - J Clin Invest VL - 109 UR - https://doi.org/10.1172/JCI0215197 DO - 10.1172/JCI0215197 ID - Duckett2002 ER - TY - JOUR AU - Guttridge, D. C. AU - Albanese, C. AU - Reuther, J. Y. AU - Pestell, R. G. AU - Baldwin, A. S. PY - 1999 DA - 1999// TI - NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1 JO - Mol Cell Biol VL - 19 UR - https://doi.org/10.1128/MCB.19.8.5785 DO - 10.1128/MCB.19.8.5785 ID - Guttridge1999 ER - TY - JOUR AU - La Rosa, F. A. AU - Pierce, J. W. AU - Sonenshein, G. E. PY - 1994 DA - 1994// TI - Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors JO - Mol Cell Biol VL - 14 UR - https://doi.org/10.1128/MCB.14.2.1039 DO - 10.1128/MCB.14.2.1039 ID - La Rosa1994 ER - TY - JOUR AU - Pikarsky, E. AU - Porat, R. M. AU - Stein, I. AU - Abramovitch, R. AU - Amit, S. AU - Kasem, S. PY - 2004 DA - 2004// TI - NF-kappaB functions as a tumour promoter in inflammation-associated cancer JO - Nature VL - 431 UR - https://doi.org/10.1038/nature02924 DO - 10.1038/nature02924 ID - Pikarsky2004 ER - TY - JOUR AU - Hayden, M. S. AU - Ghosh, S. PY - 2004 DA - 2004// TI - Signaling to NF-kappaB JO - Genes Dev VL - 18 UR - https://doi.org/10.1101/gad.1228704 DO - 10.1101/gad.1228704 ID - Hayden2004 ER - TY - JOUR AU - House, C. D. AU - Jordan, E. AU - Hernandez, L. AU - Ozaki, M. AU - James, J. M. AU - Kim, M. PY - 2017 DA - 2017// TI - NFκB promotes ovarian tumorigenesis via classical pathways that support proliferative Cancer cells and alternative pathways that support ALDH+ Cancer stem-like cells JO - Cancer Res VL - 77 UR - https://doi.org/10.1158/0008-5472.CAN-17-0366 DO - 10.1158/0008-5472.CAN-17-0366 ID - House2017 ER - TY - JOUR AU - Oeckinghaus, A. AU - Hayden, M. S. AU - Ghosh, S. PY - 2011 DA - 2011// TI - Crosstalk in NF-κB signaling pathways JO - Nat Immunol VL - 12 UR - https://doi.org/10.1038/ni.2065 DO - 10.1038/ni.2065 ID - Oeckinghaus2011 ER - TY - JOUR AU - Kucharczak, J. AU - Simmons, M. J. AU - Fan, Y. AU - Gélinas, C. PY - 2003 DA - 2003// TI - To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis JO - Oncogene VL - 22 UR - https://doi.org/10.1038/sj.onc.1207230 DO - 10.1038/sj.onc.1207230 ID - Kucharczak2003 ER - TY - JOUR AU - Boehm, J. S. AU - Zhao, J. J. AU - Yao, J. AU - Kim, S. Y. AU - Firestein, R. AU - Dunn, I. F. PY - 2007 DA - 2007// TI - Integrative genomic approaches identify IKBKE as a breast cancer oncogene JO - Cell VL - 129 UR - https://doi.org/10.1016/j.cell.2007.03.052 DO - 10.1016/j.cell.2007.03.052 ID - Boehm2007 ER - TY - JOUR AU - Perkins, N. D. PY - 2012 DA - 2012// TI - The diverse and complex roles of NF-κB subunits in cancer JO - Nat Rev Cancer VL - 12 UR - https://doi.org/10.1038/nrc3204 DO - 10.1038/nrc3204 ID - Perkins2012 ER - TY - JOUR AU - Barham, W. AU - Chen, L. AU - Tikhomirov, O. AU - Onishko, H. AU - Gleaves, L. AU - Stricker, T. P. PY - 2015 DA - 2015// TI - Aberrant activation of NF-κB signaling in mammary epithelium leads to abnormal growth and ductal carcinoma in situ JO - BMC Cancer VL - 15 UR - https://doi.org/10.1186/s12885-015-1652-8 DO - 10.1186/s12885-015-1652-8 ID - Barham2015 ER - TY - JOUR AU - Annunziata, C. M. AU - Stavnes, H. T. AU - Kleinberg, L. AU - Berner, A. AU - Hernandez, L. F. AU - Birrer, M. J. PY - 2010 DA - 2010// TI - Nuclear factor kappaB transcription factors are coexpressed and convey a poor outcome in ovarian cancer JO - Cancer VL - 116 UR - https://doi.org/10.1002/cncr.25190 DO - 10.1002/cncr.25190 ID - Annunziata2010 ER - TY - JOUR AU - Hsu, S. AU - Kim, M. AU - Hernandez, L. AU - Grajales, V. AU - Noonan, A. AU - Anver, M. PY - 2012 DA - 2012// TI - IKK-ε coordinates invasion and metastasis of ovarian cancer JO - Cancer Res VL - 72 UR - https://doi.org/10.1158/0008-5472.CAN-11-3993 DO - 10.1158/0008-5472.CAN-11-3993 ID - Hsu2012 ER - TY - JOUR AU - Hutti, J. E. AU - Shen, R. R. AU - Abbott, D. W. AU - Zhou, A. Y. AU - Sprott, K. M. AU - Asara, J. M. PY - 2009 DA - 2009// TI - Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation JO - Mol Cell VL - 34 UR - https://doi.org/10.1016/j.molcel.2009.04.031 DO - 10.1016/j.molcel.2009.04.031 ID - Hutti2009 ER - TY - JOUR AU - Barbie, T. U. AU - Alexe, G. AU - Aref, A. R. AU - Li, S. AU - Zhu, Z. AU - Zhang, X. PY - 2014 DA - 2014// TI - Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth JO - J Clin Invest VL - 124 UR - https://doi.org/10.1172/JCI75661 DO - 10.1172/JCI75661 ID - Barbie2014 ER - TY - JOUR AU - Qin, B. AU - Cheng, K. PY - 2010 DA - 2010// TI - Silencing of the IKKε gene by siRNA inhibits invasiveness and growth of breast cancer cells JO - Breast Cancer Res VL - 12 UR - https://doi.org/10.1186/bcr2644 DO - 10.1186/bcr2644 ID - Qin2010 ER - TY - JOUR AU - Scudiero, D. A. AU - Shoemaker, R. H. AU - Paull, K. D. AU - Monks, A. AU - Tierney, S. AU - Nofziger, T. H. PY - 1988 DA - 1988// TI - Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines JO - Cancer Res VL - 48 ID - Scudiero1988 ER - TY - JOUR AU - Schneider, C. A. AU - Rasband, W. S. AU - Eliceiri, K. W. PY - 2012 DA - 2012// TI - NIH image to ImageJ: 25 years of image analysis JO - Nat Methods VL - 9 UR - https://doi.org/10.1038/nmeth.2089 DO - 10.1038/nmeth.2089 ID - Schneider2012 ER - TY - JOUR AU - Nadiminty, N. AU - Dutt, S. AU - Tepper, C. AU - Gao, A. C. PY - 2010 DA - 2010// TI - Microarray analysis reveals potential target genes of NF-kappaB2/p52 in LNCaP prostate cancer cells JO - Prostate VL - 70 UR - https://doi.org/10.1002/pros.21062 DO - 10.1002/pros.21062 ID - Nadiminty2010 ER - TY - JOUR AU - Nakatsu, Y. AU - Matsuoka, M. AU - Chang, T. H. AU - Otsuki, N. AU - Noda, M. AU - Kimura, H. PY - 2014 DA - 2014// TI - Functionally distinct effects of the C-terminal regions of IKKε and TBK1 on type I IFN production JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0094999 DO - 10.1371/journal.pone.0094999 ID - Nakatsu2014 ER - TY - JOUR AU - Wang, Y. AU - Lu, X. AU - Zhu, L. AU - Shen, Y. AU - Chengedza, S. AU - Feng, H. PY - 2013 DA - 2013// TI - IKK epsilon kinase is crucial for viral G protein-coupled receptor tumorigenesis JO - Proc Natl Acad Sci U S A VL - 110 UR - https://doi.org/10.1073/pnas.1219829110 DO - 10.1073/pnas.1219829110 ID - Wang2013 ER - TY - JOUR AU - Eddy, S. F. AU - Guo, S. AU - Demicco, E. G. AU - Romieu-Mourez, R. AU - Landesman-Bollag, E. AU - Seldin, D. C. PY - 2005 DA - 2005// TI - Inducible IkappaB kinase/IkappaB kinase epsilon expression is induced by CK2 and promotes aberrant nuclear factor-kappaB activation in breast cancer cells JO - Cancer Res VL - 65 UR - https://doi.org/10.1158/0008-5472.CAN-05-1602 DO - 10.1158/0008-5472.CAN-05-1602 ID - Eddy2005 ER - TY - JOUR AU - Adli, M. AU - Baldwin, A. S. PY - 2006 DA - 2006// TI - IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M603133200 DO - 10.1074/jbc.M603133200 ID - Adli2006 ER - TY - JOUR AU - Wietek, C. AU - Cleaver, C. S. AU - Ludbrook, V. AU - Wilde, J. AU - White, J. AU - Bell, D. J. PY - 2006 DA - 2006// TI - IkappaB kinase epsilon interacts with p52 and promotes transactivation via p65 JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M607018200 DO - 10.1074/jbc.M607018200 ID - Wietek2006 ER - TY - JOUR AU - Yeo, S. K. AU - French, R. AU - Spada, F. AU - Clarkson, R. PY - 2017 DA - 2017// TI - Opposing roles of Nfkb2 gene products p100 and p52 in the regulation of breast cancer stem cells JO - Breast Cancer Res Treat VL - 162 UR - https://doi.org/10.1007/s10549-017-4149-0 DO - 10.1007/s10549-017-4149-0 ID - Yeo2017 ER - TY - JOUR AU - Kendellen, M. F. AU - Bradford, J. W. AU - Lawrence, C. L. AU - Clark, K. S. AU - Baldwin, A. S. PY - 2014 DA - 2014// TI - Canonical and non-canonical NF-κB signaling promotes breast cancer tumor-initiating cells JO - Oncogene VL - 33 UR - https://doi.org/10.1038/onc.2013.64 DO - 10.1038/onc.2013.64 ID - Kendellen2014 ER - TY - JOUR AU - Rojo, F. AU - González-Pérez, A. AU - Furriol, J. AU - Nicolau, M. J. AU - Ferrer, J. AU - Burgués, O. PY - 2016 DA - 2016// TI - Non-canonical NF-κB pathway activation predicts outcome in borderline oestrogen receptor positive breast carcinoma JO - Br J Cancer VL - 115 UR - https://doi.org/10.1038/bjc.2016.204 DO - 10.1038/bjc.2016.204 ID - Rojo2016 ER - TY - JOUR AU - Shen, R. R. AU - Hahn, W. C. PY - 2011 DA - 2011// TI - Emerging roles for the non-canonical IKKs in cancer JO - Oncogene VL - 30 UR - https://doi.org/10.1038/onc.2010.493 DO - 10.1038/onc.2010.493 ID - Shen2011 ER - TY - JOUR AU - Liu, S. AU - Cong, Y. AU - Wang, D. AU - Sun, Y. AU - Deng, L. AU - Liu, Y. PY - 2014 DA - 2014// TI - Breast Cancer stem cells transition between epithelial and mesenchymal states reflective of their normal counterparts JO - Stem Cell Reports VL - 2 UR - https://doi.org/10.1016/j.stemcr.2013.11.009 DO - 10.1016/j.stemcr.2013.11.009 ID - Liu2014 ER -