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Table 3 Results of univariate and multivariate analyses of clinicopathological factors affecting the overall survival rate following surgery

From: High expression of forkhead box protein C2 is associated with aggressive phenotypes and poor prognosis in clinical hepatocellular carcinoma

Clinicopathologic variable

Univariate analysis

Multivariate analysis

RR

95%CI

P value

RR

95%CI

P value

FOXC2 expression (low/high)

2.14

1.05–4.34

0.035a

2.21

1.06–4.57

0.033a

Age (≤65/> 65)

1.17

0.518–2.66

0.70

–

–

–

Gender (male/female)

1.13

0.485–2.62

0.78

–

–

–

Liver cirrhosis (negative/positive)

1.86

0.913–3.77

0.087

–

–

–

Differentiation (well or moderate/poor)

1.30

0.307–5.49

0.72

–

–

–

Pattern of tumor growth (Eg/Ig)

3.29

1.53–7.07

0.0023a

3.06

1.37–6.80

0.0062a

T classification (T1–3/T4)

4.33

1.82–10.34

< 0.001a

3.82

1.18–12.37

0.025a

Portal vein invasion (negative/positive)

2.19

1.03–4.65

0.042a

1.31

0.477–3.59

0.6

AFP level (normal/high)

1.24

0.529–2.91

0.62

–

–

–

PIVKA II level (normal/high)

0.749

0.323–1.73

0.50

–

–

–

  1. RR relative risk, CI confidence interval
  2. aStatistical significance is indicated by P < 0.05