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Fig. 5 | BMC Cancer

Fig. 5

From: Involvement of the CB2 cannabinoid receptor in cell growth inhibition and G0/G1 cell cycle arrest via the cannabinoid agonist WIN 55,212–2 in renal cell carcinoma

Fig. 5

Percentage of reduction in cell viability according to the Alamar Blue® assay in RCC cell lines treated with JWH-133 and WIN-55. Representative graphs showing the cannabinoid effect on RCC cells and healthy kidney epithelial cells (ASE-5063). All of the cell lines were treated with increasing concentrations (0–25 μM) of JWH-133 (a) or WIN-55 (b), and cell proliferation was measured using Alamar blue reduction for 6 days. The agonist WIN-55 reduced the proliferation of the RCC cells, while JWH-133 did not produce a similar result [* p < 0.05 vs control (0 μM or DMSO)]

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BMC Cancer

ISSN: 1471-2407

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