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Table 2 Univariate analysis for the incidence of esophageal fistula

From: Risk factors for esophageal fistula in thoracic esophageal squamous cell carcinoma invading adjacent organs treated with definitive chemoradiotherapy: a monocentric case-control study

Characteristics EF+ (N = 28) EF− (N = 88) OR 95% CI P-value
Age ≥ 65 years 13 47 0.76 0.32–1.77 0.520
Sex, male 23 79 0.52 0.16–1.72 0.286
ECOG PS 0/1 19/9 58/30 0.92 0.37–2.27 0.849
Tumor size ≥70 mma 19 47 2.07 0.82–5.23 0.123
Total circumferential lesion 20 40 3.00 1.19–7.54 0.019
Esophageal stenosis 18 56 1.03 0.42–2.50 0.950
Aorta invasion 16 38 1.75 0.74–4.14 0.200
Tracheal or bronchial invasion 24 68 1.76 0.55–5.69 0.341
WBC ≥ 10,000/μL 7 8 3.33 1.08–10.2 0.036
Hb < 12 g/dL 9 10 3.69 1.32–10.4 0.013
Alb < 3.5 g/dL 4 3 4.72 0.99–22.6 0.052
CRP ≥ 1.00 mg/dLb 19 29 4.15 1.67–10.3 0.002
  1. Abbreviations: EF esophageal fistula, OR odds ratio, CI confidence interval, WBC white blood cell, Hb hemoglobin, Alb albumin, CRP C reactive protein
  2. aData missing for one patient
  3. bData missing for two patients