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Table 7 Univariate and multivariate analysis of prognostic factors for duodenal and gastric GISTs

From: Clinicopathological features, surgical strategy and prognosis of duodenal gastrointestinal stromal tumors: a series of 300 patients

Prognostic factors

Univariate analysis

Multivariate analysis

β

Hazard ratio (95% CI)

P value

β

Hazard ratio (95% CI)

P value

DFS

 Age

−0.084

0.920 (0.517–1.638)

0.776

   

 Gender

−0.393

0.675 (0.384–1.186)

0.172

   

 Location

−2.105

0.122 (0.057–0.259)

0.000

−2.122

0.120 (0.054–0.266)

< 0.001

 Tumor size

1.451

4.268 (2.932–6.213)

0.000

1.417

4.124 (2.526–6.733)

< 0.001

 Mitotic index

1.283

3.608 (1.868–6.970)

0.000

0.928

2.528 (1.225–5.219)

0.012

 NIH risk category

1.813

6.128 (3.254–11.544)

0.000

   

DSS

 Age

0.387

1.473 (0.748–2.898)

0.263

0.759

2.136 (1.040–4.384)

0.039

 Gender

0.279

1.322 (0.668–2.614)

0.423

   

 Location

−0.718

0.488 (0.236–1.010)

0.049

−1.066

0.344 (0.164–0.725)

0.005

 Tumor size

1.297

3.658 (2.304–5.807)

0.000

1.386

3.999 (2.408–6.641)

< 0.001

 Mitotic index

1.202

3.327 (1.574–7.032)

0.002

   

 NIH risk category

1.094

2.985 (1.821–4.895)

0.000

   
  1. GIST: gastrointestinal stromal tumor; NIH: National Institutes of Health;
  2. DFS: disease-free survival; DSS: disease-specific survival; CI: confidence interval