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Table 7 Univariate and multivariate analysis of prognostic factors for duodenal and gastric GISTs

From: Clinicopathological features, surgical strategy and prognosis of duodenal gastrointestinal stromal tumors: a series of 300 patients

Prognostic factors Univariate analysis Multivariate analysis
β Hazard ratio (95% CI) P value β Hazard ratio (95% CI) P value
DFS
 Age −0.084 0.920 (0.517–1.638) 0.776    
 Gender −0.393 0.675 (0.384–1.186) 0.172    
 Location −2.105 0.122 (0.057–0.259) 0.000 −2.122 0.120 (0.054–0.266) < 0.001
 Tumor size 1.451 4.268 (2.932–6.213) 0.000 1.417 4.124 (2.526–6.733) < 0.001
 Mitotic index 1.283 3.608 (1.868–6.970) 0.000 0.928 2.528 (1.225–5.219) 0.012
 NIH risk category 1.813 6.128 (3.254–11.544) 0.000    
DSS
 Age 0.387 1.473 (0.748–2.898) 0.263 0.759 2.136 (1.040–4.384) 0.039
 Gender 0.279 1.322 (0.668–2.614) 0.423    
 Location −0.718 0.488 (0.236–1.010) 0.049 −1.066 0.344 (0.164–0.725) 0.005
 Tumor size 1.297 3.658 (2.304–5.807) 0.000 1.386 3.999 (2.408–6.641) < 0.001
 Mitotic index 1.202 3.327 (1.574–7.032) 0.002    
 NIH risk category 1.094 2.985 (1.821–4.895) 0.000    
  1. GIST: gastrointestinal stromal tumor; NIH: National Institutes of Health;
  2. DFS: disease-free survival; DSS: disease-specific survival; CI: confidence interval