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Table 5 Univariate and multivariate analysis of prognostic factors for the descending duodenal GISTs

From: Clinicopathological features, surgical strategy and prognosis of duodenal gastrointestinal stromal tumors: a series of 300 patients

Prognostic factors Univariate analysis Multivariate analysis
β Hazard ratio (95% CI) P value β Hazard ratio (95% CI) P value
DFS
 Age 0.487 1.628 (0.632–4.193) 0.313    
 Gender −0.375 0.687 (0.279–1.694) 0.415    
 Surgical procedure 1.473 4.361 (1.597–11.909) 0.004    
 Tumor size 1.445 4.240 (2.073–8.672) < 0.001 1.721 5.590 (2.144–14.570) < 0.001
 Mitotic index 1.696 5.453 (2.065–14.400) 0.001    
 NIH risk category 1.456 4.288 (1.594–11.531) 0.004    
 Adjuvant therapy 0.544 1.724 (0.367–8.103) 0.491    
DSS
 Age 0.276 1.318 (0.432–4.019) 0.627    
 Gender 0.008 1.008 (0.316–3.218) 0.989    
 Surgical procedure 1.519 4.569 (1.260–16.569) 0.021    
 Tumor size 2.142 8.515 (2.496–29.053) 0.001 1.976 7.213 (2.138–24.338) 0.001
 Mitotic index 1.567 4.792 (1.428–16.087) 0.011    
 NIH risk category 1.143 3.136 (1.150–8.552) 0.026    
 Adjuvant therapy −3.181 0.042 (0.000–212.916) 0.465    
  1. GIST: gastrointestinal stromal tumor; NIH: National Institutes of Health;
  2. DFS: disease-free survival; DSS: disease-specific survival; CI: confidence interval