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Table 5 ROC curve analysis of ZO-1 and hs-CRP

From: Increased systemic zonula occludens 1 associated with inflammation and independent biomarker in patients with hepatocellular carcinoma

Parameters Cut off value Sensitivity (%) Specificity (%) AUC 95% CI LR+ LR-
ZO-1 (pg/ml) 472.99 76.92 80.00 0.8692 0.766 – 0.972 3.84 0.28
hs-CRP (mg/L) 9.2 86.67 85.00 0.8767 0.776 - 0.976 5.77 0.15
  1. AUC area under curve, CI confidence interval, hsCRP high sensitivity C-reactive protein, LR+ positive likelihood ratio, LR- negative likelihood ratio, ROC receiver operator characteristics