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Table 2 Location of non-synonymous mutations in the conserved domains in the 46 patients with oral squamous cell carcinoma

From: Mutation allele frequency threshold does not affect prognostic analysis using next-generation sequencing in oral squamous cell carcinoma

  1. Note: Molecular characteristics of the detected mutations for the targeted genes. The p53 DNA-binding domain was the major conserved domain in 28 patients (60.9%), and the notch1 EGF-like repeats domain was the second major conserved domain in 13 patients (28.3%), followed by the caspase homology domain of caspase 8 in five patients (10.9%), tetramerization motif of p53 in four patients (8.7%), and ankyrin repeats of p16 in four patients (8.7%)