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Fig. 5 | BMC Cancer

Fig. 5

From: Using high throughput microtissue culture to study the difference in prostate cancer cell behavior and drug response in 2D and 3D co-cultures

Fig. 5

C42B cell Docetaxel drug response in mono- and co-cultures with bone marrow stromal cells. Luciferase-expressing C42B cells were seeded in mono- or co-cultures with stromal cells (BMSC or adipocytes) either in 2D monolayer cultures (a) or in 3D microtissue cultures (b). Results are represented as a percentage of the vehicle control values. Similar results were obtained in three, including with two BMSC donors, independent experiment each having four replicate cultures n = 4. Statistical significance was performed using two-way ANOVA compared to the corresponding control mono-culture value (* P < 0.05, ** P < 0.01 and *** P < 0.0001)

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BMC Cancer

ISSN: 1471-2407

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