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Fig. 2 | BMC Cancer

Fig. 2

From: Unmasking of intracranial metastatic melanoma during ipilimumab/nivolumab therapy: case report and literature review

Fig. 2

Axial post-contrast FSPGR brain MRI was performed 3 months after the initiation of ipi/nivo in the setting of new neurologic symptoms, revealing 6 new enhancing parenchymal lesions, the largest in the right parietal lobe (a, arrow). Multiple additional foci of chronic hemorrhage without associated visible enhancement are demonstrated on susceptibility-weighted imaging (b, arrow). Concurrent thoracic CT revealed interval decrease in size and contrast enhancement of several axillary and mediastinal lymph nodes (compare arrows in e with f). Post-contrast MRI performed one month later showed marked decrease in the size of the right parietal lesion (c, arrow), and resolution of all of the previously enhancing lesions. The patient was tapered off steroids without significant change in imaging after four months (d, arrow)

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