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Fig. 4 | BMC Cancer

Fig. 4

From: γ-Tocotrienol induces apoptosis in pancreatic cancer cells by upregulation of ceramide synthesis and modulation of sphingolipid transport

Fig. 4

Analysis of the effect of GT3 treatment on the expression levels of ceramides C16, C24:1 and C24. A. LC/MS of C16, C24:1 and C24 ceramides in MIA PaCa-2 cells (a), and HPDE-E6E7(b) dihydroceramides (c and d), and sphingomyelin (e and f ) treated with dissolution vehicle (control) or 40μM GT3. Results are shown as pmol of each indicated

sphingolipid/mg of protein in the sample analyzed. The values shown are the averages ± standard deviations obtained from three independent experiments. * p <0.05, significant difference

between control and GT3 treated cells

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