Fig. 3From: γ-Tocotrienol induces apoptosis in pancreatic cancer cells by upregulation of ceramide synthesis and modulation of sphingolipid transport Analysis of the effect of GT3 treatment on cellular levels of ceramide, dihydroceramide, and sphingomyelin. A. LC/MS analysis of sphingolipids present in theplasma membrane for ceramides (a), dihydroceramides (b), and sphingomyelin (c), in MIA Paca-2, and HPDE-E6E7 cells treated with dissolution vehicle (control) or 40 μMGT3. Results are shown as pmol of each indicated sphingolipid / mg of protein in the sample analyzed. The values shown are the averages ± standard deviations obtained from three independentexperiments. * p <0.05, significant difference between control and GT3 treated cellsBack to article page