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Table 3 Patient characteristics according to activated macrophage recruitment in SHH

From: M1 macrophage recruitment correlates with worse outcome in SHH Medulloblastomas

Macrophage Polarization CD86 (M1 macrophages)   CD163 (M2 macrophages)
  High Expressersa Low Expressersb   High Expressersa Low Expressersb
Number 12 11   12 11
Mean 6.4 ± .6 2.1 ± .3   11.2 ± .4 4.6 ± .7
Age 5.0 ± 1.1 4.6 ± 1.5   5.7 ± 1.4 4.0 ± 1.2
M:F 7:5 5:6   7:5 5:6
Lateral tumor location 7 (30%) 7 (30%)   8 (35%) 6 (26%)
Gross total resection 10 (43%) 6 (26%)   9 (39%) 7 (30%)
Large residual tumor (> 1.5cm2) 1 (4%) 3 (13%)   2 (9%) 2 (9%)
Leptomeningeal Seeding 3 (13%) 2 (9%)   3 (13%) 2 (9%)
  1. aHigh expressers indicates patients with greater than or equal to median count.
  2. bLow expressers indicates patients with lower than median count