Fig. 6
From: Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells
Growth inhibition and PARP levels upon combination treatment of selumetinib and AZ628. a Cell lines were treated with different concentrations of AZ628 for 10 days (mean values +/− SEM). b Combination indices (CI) were calculated by CompuSyn Software from the data of viability assays of selumetinib and AZ628 combination treatment (data not shown). c PARP cleavage activity upon selumetinib and AZ628 single agent or combination treatment