Fig. 4
From: Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells
Cell migration analysis by long-term video microscopy. Sorafenib (3 μM) and selumetinib (500 nM) combination treatment decrease migratory ability in non-V600 BRAF mutant cell lines. Average net displacement was determined between 48 and 60 h after the treatment. Data is shown as mean +/− SEM of at least three independent measurements (*p ≤ 0.05, * * p ≤ 0.01, * * * p ≤ 0.001)