Table 3 Efficacy evaluation
Patient no. | Evaluation (RECIST ver 1.1) | Time to response (days) | Duration of response (days) | PFS (days) | OS (days) | |||
|---|---|---|---|---|---|---|---|---|
Target response | Overall response | Surgical response | ||||||
Cohort 1 | HF-1-02 | SD | PD | 119 | 150 | |||
HF-1-04 | SD | PD | 91 | 465 | ||||
HF-1-05 | PR | PR | CR | 48 | 288 | 335 | 611 | |
Cohort 2 | HF-2-01 | SD | SD | 663 | 1211 | |||
HF-2-02 | PR | PR | CR | 13 | 444 | 456 | 1189 | |
HF-2-03 | SD | SD | 48 | 336 | ||||
Cohort 3 | HF-3-02 | SD | SD | 217 | 694 | |||
HF-3-03 | SD | SD | 69 | 273 | ||||
HF-3-04 | PR | PR | 34 | 156 | 189 | 255 | ||