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Fig. 8 | BMC Cancer

Fig. 8

From: Alterations in NO- and PGI2- dependent function in aorta in the orthotopic murine model of metastatic 4T1 breast cancer: relationship with pulmonary endothelial dysfunction and systemic inflammation

Fig. 8

Changes in 6-keto PGF concentration in effluents from aortic rings during 27 min of incubation in Krebs buffer with no inhibitor and in the presence of COX-1 selective inhibitor DuP-697 (1 μM) or nonselective COX-1 and COX-2 inhibitor indomethacin (5 μM). Results are expressed as mean ± SEM, n = 5–6, * indicates p < 0.05; ** indicates p < 0.01

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