Fig. 2

Box plots for MTV and ASP in different stages and TG/TL. In the upper row, box plots for MTV and ASP are separated only by different stages or TG/TL; significant differences between subgroups are highlighted (*p < 0.05; **p < 0.01; ***p < 0.001). Please note that only one patient had stage I disease which was therefore excluded from comparison. In the lower row, box plots are further separated by AR (dark grey) or IR (light grey); due to the smaller sample size, significance of the differences was not tested. ASP, asphericity; MTV, metabolic tumor volume, TG/TL, treatment group/level